The mission of the Mass Spectrometry Research Center (MSRC) is to bring state-of-the-art mass spectrometry expertise, methodology, and instrumentation to researchers at Vanderbilt University and Vanderbilt University Medical Center. The MSRC is located on the 9th floor in Medical Research Building III. Support for the facility comes from service cores affiliated with NIH-funded Program Projects and Research Centers, service fees charged to unaffiliated investigators and direct institutional support from Vanderbilt University.
The Proteomics Laboratory resides within the Mass Spectrometry Research Center and provides state-of the-art MS instrumentation and analytical methods to analyze proteins and proteomes. High performance LC-MS instruments and expertise provide exceptional flexibility in analytical proteomics approaches, which are integrated with powerful bioinformatics tools to mine and assemble proteomics data.
The Proteomics Core lab (3,600 sq. ft.) has eight LC-MS/MS instruments, including two LTQ ion traps, a TSQ Vantage triple quadrupole mass spectrometer, two Q Exactive Plus Orbitrap instruments, an Orbitrap Velos with ETD, an Orbitrap Exploris 480 mass spectrometer, and a Waters Xevo with HDX capabilities.
Duties and Responsibilities
Execution of proteomics workflows
Follow specific workflows for sample preparation including protein digestion, peptide labeling, and sample clean-up
Preparation of capillary LC columns
Downstream bioinformatics analysis using software for protein identification and quantification
Operation and basic maintenance of LC-MS/MS instrumentation
Operation of instrument software for data acquisition
Day-to-day maintenance of mass spectrometry instrumentation
Routine laboratory maintenance
Biological waste disposal
A Bachelor's degree in physical or biological sciences is necessary
At least two years of post-graduate experience or equivalent in a research or analytical setting is necessary
Experience in protein chemistry, protein/peptide analysis via nanoflow HPLC - mass spectrometry, and mass spectrometry data analysis is preferred
Experience with molecular, biochemical, or cell biological techniques will also be considered
Strong organizational skills are necessary
Ability to work independently is necessary
Ability to learn and assist in development of new protocols/technologies in an evolving field is necessary
Commitment to Equity, Diversity, and Inclusion
At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff. Our commitment to diversity makes us who we are. We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education.
Vanderbilt University is an equal opportunity, affirmative action employer. Women, minorities, people with disabilities and protected veterans are encouraged to apply.
Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.
Internal Number: 10000024
About Vanderbilt University
Vanderbilt University is a center for scholarly research, informed and creative teaching, and service to the community and society at large. Vanderbilt will uphold the highest standards and be a leader in the quest for new knowledge through scholarship, the dissemination of knowledge through teaching and outreach, and the creative experimentation of ideas and concepts. In pursuit of these goals, Vanderbilt values most highly intellectual freedom that supports open inquiry, equality, compassion, and excellence in all endeavors.