The Feinberg School of Medicine’s Department of Dermatology at Northwestern University invites applications for postdoctoral candidates with strong research skills and an interest in working in a basic research, preclinical and translational environment. Work is focused on the development of novel safe approaches to the glucocorticoid receptor – targeting therapies to reduce notorious metabolic and atrophic side effects of glucocorticoids. As a member of our team, the applicant will have the opportunity to participate in work focused on the identification of specific molecular drivers of steroid-induced skin atrophy; search for the anti-atrophogenic compounds to develop skin protectors against steroids and ageing; and studies of molecular functions of already established atrophogene REDD1/DDIT4 in keratinocytes, adipocytes, and other skin cells and its interaction with steroid hormone receptors.
The applicant will use wide range of approaches: from molecular and cellular biology (including CRISPR/Cas9 gene targeting) to bioinformatics. Strong experience in molecular biology as well as experience in steroid hormone receptors, skin biology, and bioinformatics analysis is a plus.
Lab maintenance, ordering materials
Conducting laboratory experiments
Maintaining animals, breeding, genotyping for experiments
Help write grants
Supervising students and colleagues
Help write and prepare manuscripts
PhD training in molecular or cell biology, biochemistry. > 4 years of laboratory experience
Minimum Competencies: (Skills, knowledge, and abilities.)
Computer skills to graph data and analyze results
Exposure to animal handling
Sterile cell culture
Experience with biochemistry and/or molecular biology
Molecular biology skills
Experience with CRISPR/Cas9 gene targeting
Understanding of receptor signaling pathways
Understanding of skin biology
Preferred Competencies: (Skills, knowledge, and abilities)
Competency in bioinformatics analyses
Familiar with steroid hormone receptors
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 38485
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.