Why Work at BNL? Brookhaven National Laboratory (www.bnl.gov) delivers discovery science and transformative technology to power and secure the nation's future. Brookhaven Lab is a multidisciplinary laboratory with seven Nobel Prize-winning discoveries, 37 R&D 100 Awards, and more than 70 years of pioneering research. The Lab is primarily supported by the U.S. Department of Energy's (DOE) Office of Science. Brookhaven Science Associates (BSA) operates and manages the Laboratory for DOE. BSA is a partnership between Battelle and The Research Foundation for the State University of New York on behalf of Stony Brook University.
The mission in the Biology Department at Brookhaven National Laboratory seeks to unravel and fully describe the complexities of biological systems - from how plants make oils and other products to the role of proteins in disease.
The Brookhaven National Laboratory has openings for one year term (with annual renewal contingent upon satisfactory performance and continued funding) Postdoctoral Research Associates to develop an integrated multi-scale bioimaging workflow for detecting, capturing, imaging, and analyzing biological processes for sustainable and secure bioenergy. Scientific topics of the project include, but not limited to, metal homeostasis and stress resistance, lipid biosynthesis and metabolism, plant-microbe interactions, and plant cell wall structure and biosynthesis. The incumbents will work closely with scientists from the Biology Department, National Synchrotron Light Source II (NSLS-II), Laboratory of BioMolecular Structure (LBMS) Cryo-EM facility, Computational Science Initiative (CSI) as well as Yale University. We invite talented candidates to apply for this opportunity to carry out technology development and scientific research projects in the area of imaging biological processes to understand biological complexity for bioenergy.
This project will utilize the state-of-the-art Brookhaven Lab facilities NSLS-II on X-ray imaging, CFN (Center for Functional Nanomaterials) on light microscopy, LBMS on electron tomography, and CSI on advanced computational infrastructure and algorithms. NSLS-II is a world-leading synchrotron facility that produces high-flux, and low-emittance X-rays for solving a wide range of biological problems via diffraction, scattering, and imaging capabilities. CFN explores the unique properties of materials and processes at the nanoscale supported by the operation of high-end instruments from material fabrication and characterization to theory and computation. LBMS provides imaging capabilities for studying biological structures and processes at sub-nanometer resolutions. The integration of lights, x-rays, and electrons as imaging tools will allow for studying transient biological structures and processes at an unprecedented resolution. This position has a high level of interaction with an international and multicultural scientific community.
Essential Duties and Responsibilities:
Prepare biological tissues and cellular samples for imaging data acquisition and analysis.
Develop sample handling tools and protocols for integrated multi-scale imaging data acquisition using light microscopy, x-ray, and electron tomography.
Develop optimized methods and procedures to mill tissue and cell samples for electron tomography.
Document and disseminate research results through publications and conduct research presentations at meetings and conferences.
Required Knowledge, Skills, and Abilities:
Ph.D. in biophysics, chemistry, biochemistry, physics, biostatistics, bioengineering, cell biology, or a related field
Demonstrated experience in one or more of tissue/cell culture, gene expression, cellular and tissue imaging, instrumentation for bioimaging, imaging data acquisition, and image data analysis
Demonstrated publication record in a peer-reviewed journal
Clear and concise oral and written communication skills and effective interaction in a team environment
Preferred Knowledge, Skills, and Abilities:
Experience in using a confocal light microscope such as Leica TCS SP5 and Olympus IX81
Familiar with x-ray diffraction or imaging data acquisition at a synchrotron beamline
Experience in using a transmission electron microscope such as Titan Krios, Talos and JEM2100F
Experience in the development of instruments and protocols toward automation
Skills in shell scripting and programming
Experience in machine learning including deep learning for feature recognition and segmentation
Experience in using a cryoFIB for electron tomography
Experience in gene expression in Tabaco leaves, Arabidopsis, or other land plants
BNL policy requires that research associate appointments be made to individuals who have received their doctorate within the past five years
Initial one-year term appointment subject to renewal contingent on satisfactory performance and funding
National travel may be required
Candidates should submit a CV, a brief description of research interests, and contact information for three references.
At Brookhaven National Laboratory we believe that a comprehensive employee benefits program is an important and meaningful part of the compensation employees receive. Our benefits program includes, but is not limited to:
Paid Parental Leave
Swimming Pool, Weight Room, Tennis Courts, and many other employee perks and benefits
Brookhaven National Laboratory (BNL) is an equal opportunity employer that values inclusion and diversity at our Lab. We are committed to ensuring that all qualified applicants receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, status as a veteran, disability or any other federal, state or local protected class.
BNL takes affirmative action in support of its policy and to advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities. We ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
*VEVRAA Federal Contractor
Internal Number: 2541
About Brookhaven National Laboratory
Brookhaven National Laboratory is a multipurpose research institution funded primarily by the U.S. Department of Energy’s Office of Science. Located on the center of Long Island, New York, Brookhaven Lab brings world-class facilities and expertise to the most exciting and important questions in basic and applied science—from the birth of our universe to the sustainable energy technology of tomorrow. We operate cutting-edge large-scale facilities for studies in physics, chemistry, biology, medicine, applied science, and a wide range of advanced technologies. The Laboratory's almost 3,000 scientists, engineers, and support staff are joined each year by more than 4,000 visiting researchers from around the world. Our award-winning history, including seven Nobel Prizes, stretches back to 1947, and we continue to unravel mysteries from the nanoscale to the cosmic scale, and everything in between. Brookhaven is operated and managed by Brookhaven Science Associates, which was founded by the Research Foundation for the State University of New York on behalf of Stony Brook University, and Battelle, a nonprofit applied science and technology organization.