The Department of Laboratory Medicine and Pathology serves as a regional resource for clinical laboratory services required for patient care, research and educational programs in laboratory medicine and pathology. The department now employs 900 people who work at the award-winning University of Washington Medical Center, Harborview Medical Center and many other clinical and research facilities in the area. The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement and natural beauty.
The Department of Laboratory Medicine and Pathology has an outstanding opportunity for a full-time, day shift RESEARCH SCIENTIST/ENGINEER-SENIOR . This individual will oversee and coordinate the research development and validation of new genomic based diagnostics testing in the Genetics Division.
Responsible for the technical and development of the research projects and experiments in Genetics, to support research in optimizing of high-complexity molecular assays, and process improvement that will be used for the Genetics Division, including liaising with the Molecular Hematopathology laboratory. This will include coordinating research efforts in laboratory automation of next-generation sequencing based assays across the division.
Lead automation efforts in the Genetics research laboratories involving liquid handlers.
Develop process improvements in workflow of next generation sequencing based tests.
Develop and implement clinical research validation to be used for genetic and genomic test services based on next-generation sequencing and related technologies.
Facilitate and lead the research process of streamlining and harmonization of wet bench aspects of next-generation sequencing workflows across Genetics Division laboratories.
Plans, develops, and coordinates research and development of technical workflows and facilities of Genetics Division laboratories.
Oversee the creation of technical development documentation (validation document, procedures) for new and updated Genetics Division tests from research to specification required by regulatory agencies, including CAP, CLIA, FDA, Study Sponsors, and PIs.
Negotiate with vendors for reagents and instrumentation needed for expanded next-generation sequencing services across the Genetics Division laboratories.
Review current Genetic Division technical development plans and assist in planning for annual division research and development technical goals and objectives.
Interact with laboratory clients (physician and other medical providers) related to aspects of technical development.
Assist in test interpretation and test reporting from research validated tests.
Review high-complexity quality control data for Genetics Division laboratories.
Participate, as needed, in teaching of undergraduates, graduate students, residents, and fellows.
Participate in research and scholarship related to the Genetics Division leadership.
Other duties as assigned.
Full supervisory responsibilities for staff; hires, trains, conducts performance evaluations, and works with Human Resources to discipline and/or terminate employee(s), when necessary.
Masters or Ph.D. (desired) in Genetics, Molecular Cell Biology, Biochemistry, or other Life Sciences, with at least 6 years or more of Genetics or Molecular Biology experience; OR
Equivalent experience may substitute for degree requirement.
Experience in molecular biology methods and data analysis.
Experience with instrumentation associated with next-generation sequencing (NGS) including Illumina sequencing instruments and automated liquid handling instruments used in NGS.
Strong teamwork and interpersonal skills. Strong organizational and documentation skills suitable to a clinical laboratory environment.
Extensive experience with next-generation sequencing methods and data analysis.
Experience in clinical diagnostics. Management experience in a laboratory setting.
Experience with next-generation sequencing and/or cell-free DNA laboratory methods.
Understanding of the principles of cancer genetics and clinical molecular diagnostics.
Familiarity with standard bioinformatics tools and databases.
UW Medicine includes Harborview Medical Center, UW Medical Center - Montlake, UW Medical Center - Northwest, Valley Medical Center, UW Neighborhood Clinics, UW Physicians, UW School of Medicine, and Airlift Northwest.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.