The Carvill Lab in the Department of Neurology is seeking a new research technologist to join our team. Our research focuses on the genetic and epigenetic basis of epilepsy; we use numerous genomic technologies as well as iPSCs to study pathogenic mechanisms towards discovering new precision therapies. We are seeking a technician to work on multiple NIH and Foundation-funded research projects, as well as to oversee the general day to day running of the lab. Learn more about our work and the team here: https://sites.northwestern.edu/carvilllab/
Participates in design and execution of research lab projects. Conducts experimental tests and procedures and processes and analyzes data. Reviews and revises existing research methodologies and may develop new methodologies, mathematical and/or computer models for predicting data. May ensure overall lab compliance with all associated rules and regulations.
Following overall research objectives, independently designs, plans, conducts and troubleshoots experiments.
Evaluates protocols and data obtained from groups of experiments and recommends changes to processes, procedures and techniques to improve quality and validity of results based upon overall project objectives.
Using an advanced level of skill, completes the following activities:
DNA, RNA, Protein isolation, purification and expression
analysis, Western blotting
Cloning, mapping and sequencing of DNA
Recombinant virus production and purification
Cell culture, cell isolation
Database management of colony
Observes experiments, collects, records, summarizes, analyzes and interprets research data.
Collates relevant mathematical results.
Prepares complex tables reflecting relationships of multiple tests.
Draws scientific conclusions.
Writes portions of grant applications.
Co-authors scientific papers.
Negotiates purchases with vendors.
Maintains and updates portions of grant budgets.
Tracks and summarizes lab supply expenses.
Verifies accuracy of invoices.
Orders and/or maintains inventory of reagent, mice and/or lab supplies.
Trains and directs other lab EEs and/or students in research techniques and procedures.
Performs other duties as assigned.
Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience and 3 years' lab/bench or other relevant experience required; OR
Successful completion of a full course of study in an accredited college or university leading to a master's or higher degree in a scientific major or related; OR appropriate combination of education and experience and 1 year lab/bench or other relevant experience.
Minimum Competencies: (Skills, knowledge, and abilities.)
Working knowledge of computers and software (Microsoft Word, Excel) basic statistics; ability to work independently, Strong organizational skills and multitasking
Bachelor’s or Master’s degree in the life sciences
Previous experience working in a research lab (minimum 3 years) is essential
Preferred Competencies: (Skills, knowledge, and abilities)
Experience with iPSC maintenance and differentiation, preferably to a neuronal lineage.
Genome editing with CRISPR/Cas9
Expertise in next generation sequence technologies for instance: targeted/exome/genome sequencing, RNA-seq, ChIP-seq, ATAC-seq, scRNAseq or similar.
Track record of training junior scientists.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 40051
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.