The Pap Research Institute is dedicated to building a state-of-the-art research facility with a focus on studying numerous childhood diseases, such as diabetes, neurological disorders, hemophilia, pediatric cancer and metabolic disorders. The overall focus of our research program is on the development of novel therapies for disorders with currently inadequate treatments. In order to complement the cell transplantation expertise of the adjacent Oregon Stem Cell Center, we will focus our efforts on building the promising area of gene therapy. In addition, we have a particular interest in disorders of the blood, including leukemia. Over time, we plan to build a powerful synergistic environment capable of developing new stem cell transplantation and new gene transfer platforms for the treatment of childhood diseases.
We are looking for an enthusiastic, highly-motivated, and dedicated PhD scientist to join our team. Our lab is focused on improving treatment and prevention strategies for and ultimately ending the neonatal inflammatory condition necrotizing enterocolitis (NEC). We are interested in extracellular vesicles (EVs) as carriers of information into and throughout the body, as well as mechanisms that regulate EV genesis and cargo loading. We aim to understand how EVs derived from food, the intestinal microbiome, and the intestinal cells themselves influence human health and disease in NEC and beyond. We use human patient samples, including novel 3D patient-derived enteroids, genetic mouse models, and cutting-edge molecular biology, extracellular vesicle, and imaging techniques to answer critical questions. Our research is highly translational with the ultimate aim of taking bench findings back to educate bedside treatments and practices.
Following the scientific method to ask and answer scientific questions
Working as part of a team
Strong oral and written communication skills
Troubleshooting and problem-solving skills
Open and willing to learn new skills
Mentoring junior colleagues
Extracellular vesicle biology
Mouse models experience
Molecular biology skills
Please upload CV or resume and cover letter.
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