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Post Doc for Computational Protein Sequence-to-Function Discovery
Brookhaven National Laboratory
Why Work at BNL? Position Description CSI has an opening for a post-doc to participate in multi-disciplinary development of new tools to facilitate sequence-to-function discovery. BNL is the home to several state-of-art research facilities, including synchrotron beamlines at NSLS-II (https://www.bnl.gov/ps/lifesciences/), cryo-EM at the new Laboratory for BioMolecular Structures (LBMS, https://www.bnl.gov/cryo-em/), and computation at the Computational Science Initiative (CSI, https://www.bnl.gov/compsci/). We have initiated a project, with participation from investigators from Biology Department, CSI, LBMS and NSLS-II, to develop integrative data analysis to maximize the impact of the data collected at the BNL facilities. More specifically, computation and modeling will be used to help put in context multi-scale data from different experimental methods, including crystallography, solution scattering, and cryo-EM. Together with other team members, the candidate will carry out proof-of-concept research using a series of pre-selected test cases, including determining mechanistic understanding for a novel nucleotide-dependent fungal zinc transferase involved in protein biogenesis and studying the dynamics of heme-zinc cooperativity in a newly discovered cyanobacterial heme protein. This work will help establish standard workflows that will become more broadly applicable to user projects at NSLS-II and LBMS. The long-term goal is to eventually establish a new research center that interfaces external users with the research capabilities at BNL. This position has a two-year term. Extension to a third year will depend on satisfactory performance and funding.
Essential Duties and Responsibilities:
Position Requirements Required Knowledge, Skills, and Abilities:
Preferred Knowledge, Skills, and Abilities:
OTHER INFORMATION: (add if applicable)
POST-DOC BNL policy requires that research associate appointments be made to individuals who have received their doctorate within the past five years. At Brookhaven National Laboratory we believe that a comprehensive employee benefits program is an important and meaningful part of the compensation employees receive. Our benefits program includes, but is not limited to:
Brookhaven National Laboratory (BNL) is an equal opportunity employer that values inclusion and diversity at our Lab. We are committed to ensuring that all qualified applicants receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, status as a veteran, disability or any other federal, state or local protected class.
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