Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments.
About the Department of Pathology
Comprised of extraordinary faculty and staff, our mission is to improve the diagnosis, treatment and basic understanding of human disease. We accomplish this through our clinical services, research, and training the future leaders in pathology and related fields.
An LSRP position is available in the laboratory of Dr. Robert West in the Department of Pathology at Stanford University.
Our lab applies cutting-edge high-throughput methods to study soft tissue sarcomas. We seek to understand the molecular underpinnings of these cancers, with the goal of developing new diagnostic, prognostic, and/or predictive biomarkers and therapeutic targets that can be applied in clinical practice. Our research interests include the genetic, epigenetic, and transcriptomic characteristics of various types of soft tissue tumors including leiomyosarcoma and leiomyoma. The LSRP will be involved in a research project that aims to perform molecular analyses of these tumors on a single cell level, in order to better understand the biology, evolution and clinical behavior of these tumors, and to identify novel therapeutic strategies. Specifically, LSRP will be making single cell and single nuclei preparations from different types of soft tissue tumors, doing molecular profiling (DNA sequencing, RNA sequencing, and methylome profiling) and apply computational biology methods to analyze and interpret the next generation sequencing data. The position also includes lab management tasks such as ordering supplies, maintaining our slide/block/tissue inventory, keeping detailed lab records, and adhering to safety regulations.
We welcome candidates with a growth mindset, interest in a variety of cancer research questions related to molecular underpinnings of disease, and a willingness to take on challenging learning opportunities.
In addition to comparable research compensation, candidates will have the opportunity to learn and to develop their C.V. or resume through research publications and presentations.
Plan and perform experiments in support of research projects in the laboratory based on knowledge of scientific theory. Interpret and perform basic analyses of the results.
Apply protocols for preparation of single cell and/or single nuclei suspension from fresh, frozen, and/or formalin fixed paraffin embedded tissue and subsequent library construction for next generation sequencing (sequencing performed at a core laboratory). Sequencing data generated can be analyzed using existing software programs. Downstream experiments may include designing a targeted sequencing test, in situ hybridization, and/or immunohistochemical biomarker testing.
Review literature on an ongoing basis to remain current with new procedures and related research.
Apply the theories and methods of molecular and/or computational biology to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols under supervision of a senior researcher.
Maintain detailed records of experiments and outcomes.
Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
Help with general lab maintenance as needed; maintain lab stocks, manage chemical inventory and safety records, and provide general lab support as needed.
Assist with orientation and training of new staff or students on lab procedures or techniques.
*- Other duties may also be assigned
A bachelor's degree in biological sciences or a related field.
Previous experience or established knowledge of basic laboratory techniques in molecular biology.
Strong analytical skills and excellent judgment.
Must be accurate, efficient, organized and have excellent record keeping abilities.
Ability to work with team members in a cooperative fashion.
Excellent communication skills.
Education & Experience (REQUIRED):
Bachelor's degree in related scientific field.
Knowledge, Skills and Abilities (REQUIRED):
General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
Ability to maintain detailed records of experiments and outcomes.
General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
Ability to work under deadlines with general guidance.
Excellent organizational skills and demonstrated ability to accurately complete detailed work.
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
Must have correctible vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
May require working in close proximity to blood borne pathogens.
May require work in an environment where animals are used for teaching and research.
Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and business needs.
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.
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Located between San Francisco and San Jose in the heart of Silicon Valley, Stanford University is recognized as one of the world's leading research and teaching institutions. Leland and Jane Stanford founded the University to "promote the public welfare by exercising an influence on behalf of humanity and civilization." Stanford opened its doors in 1891, and more than a century later, it remains dedicated to finding solutions to the great challenges of the day and to preparing students for leadership in a complex world. The University's thriving diverse community is comprised of nearly 7000 undergraduate students, 12000 graduate students, 2000 faculty members, 1900 postdoctoral scholars, and over 11,000 academic and administrative staff in seven schools including several interdisciplinary research centers and institutes. The campus spreads over 8000 contiguous acres and nearly all undergraduates live on campus. Stanford offers bachelor's and master's degrees in addition to doctoral degrees (PhD, MD, DMA and JD) plus a number of professional and continuing education programs and certifications. More at http://facts.stanford.edu and http://www.stanford.edu. Stanford is an equal empl...oyment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford also welcomes applications from others who would bring additional dimensions to the University’s research, teaching and clinical missions.