Bioinformatics Research Analyst - Neurosurgery - 49748

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

This position is in the Department of Neurosurgery. The position is located at McMIllan Building. This position is for the Medical School Campus.

The Department of Neurological Surgery provides comprehensive patient care services, from diagnosis through treatment. In existence since 1919, the Department offers its services at Barnes-Jewish Hospital and St. Louis Children's Hospital, both nationally recognized for excellence. Both hospitals are the most technologically advanced in the region, offering patients the latest in diagnosis and treatment.

This position is grade R09.

Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account.  If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor.  To attach these documents, go to:  My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

This position is eligible for full-time benefits.  Please click the following link to view a summary of benefits:  https://wustl.box.com/s/8wkhs25yssf0775x9d6nd6vqa7obpth7.

This position is full-time and works approximately 40 hours per week.  

POSITION SUMMARY: 

A Bioinformatics Research Analyst position in single cell cancer genomics is available at Washington University School of Medicine in St. Louis. The analyst will use computational approaches to analyze, integrate, and interpret large-scale genomic data -- with an emphasis on single-cell RNA-sequencing and spatial transcriptomics data -- to study heterogeneity and gene regulatory networks in cancer. Current projects address topics such as the interplay of genetic, transcriptional, spatial, and immunological heterogeneity in brain tumors such as glioblastoma. The analyst will work in a highly collaborative environment, involving extensive interaction with faculty, molecular biologists, computational biologists, programmers, and clinicians. The position assists in developing and conducting research projects, including experiment design, data analysis, and documentation of experiment results.

PRIMARY DUTIES AND RESPONSIBILITIES

1. Designs, develops, and implements:

• Algorithms and computer software for omics-based data sets [high-throughput, massively parallel genomic data, especially single-cell and bulk RNA-seq data].
• Data management and analysis solutions that aid in the storage, investigation, and dissemination of large data sets.
• Independent research projects, including design of research protocols and development of procedures for the collection, verification, and management of data.

2. Performs complex systems analysis of data and writes interpretative reports.
3. Evaluates commercial and academic bioinformatics software.
4. Trains other researchers on the everyday use of analysis software and research databases.
5. Assists with grant preparation and reporting of methods, data, and results.
6. Solves practical problems relating to difficulties with equipment or test subjects; suggests technical or procedural improvements in testing methods.

Bachelor’s degree in computer science, bioinformatics, biostatistics, or a related field plus two years of experience; OR a master’s degree in computer science, bioinformatics, biostatistics, or related field experience; OR combined education and experience of seven years.

• Master’s or Ph.D. degree in computer science, statistics, computational biology, applied math, physics, bioinformatics, genomics, or a related field.
• Proficiency in the *nix shell and at least one programming language (Python, R, Perl, C, etc).
• Experience with statistical software packages in R and/or Python.
• Experience with quantitative analysis of large, multidimensional data sets, particularly gene expression and/or next-generation sequencing data.
• Working knowledge of genetics and cell biology.
• Interest in Machine Learning.
• Strong oral and written communication skills.
• Ability to solve scientific and quantitative problems creatively.
• Ability to work effectively in a team.

The hiring range for this position is $19.57 - $26.41 per hour.