Oregon Health & Science University is a nationally prominent research university and Oregons only public academic health center. It educates health professionals and scientists and provides leading-edge patient care, community service and biomedical research.
Fellows will have the opportunity to interact/collaborate with researchers from genetics, neurosciences, the new computational biology program, and clinical research programs focused on neurodevelopmental disorders.
A Postdoctoral Scholar position with a bioinformatics/computational, experimental, or dual focus is available immediately in the laboratory of Dr. Brian J. ORoak, Department of Molecular and Medical Genetics at Oregon Health & Science University (OHSU) for highly motivated individuals. Highlights of Dr. ORoaks past research successes include: pioneering trio-based exome sequencing in simplex autism and developing new technologies for rapid and economical targeted resequencing.
We are building on this experience by forming a strong and diverse research group focused on developing and implementing cutting-edge methods and technologies for discovery and replication, molecular diagnosis, functional dissection of pathways, and targeted therapeutics for neurodevelopmental and related disorders. This work has the potential to dramatically improve the lives of individuals affected with these currently untreatable disorders through early intervention and biologically based personal therapies.
Areas of interest include: genomics, single-cell genomics, modeling of neurodevelopmental disorders in stem cell (iPSC) and animal systems, massively parallel functional assays, and bioinformatics.
In particular, there is an immediate need for a fellow with next-generation sequence analysis experience to lead a project exploring the role of germline mutations and somatic mosaicism in autism and other neurodevelopmental disorders (e.g. neural tube detects), for which long-term funding currently exists. This would build on our work recently published in the AJHG (see Krupp et al. 2017).
Salary for this position aligns with the NIH Scale.
PhD, MD or MD/PhD in neuroscience, cell/molecular biology, genetics or related field
Strong interest in developmental neuroscience
Demonstrated ability to work independently and learn new techniques quickly
Candidates must be well organized, self-motivated and dependable
Excellent communication skills with the ability to plan, document, analyze and report data
Intensive training in the areas of genetics/genomics, computer science, or bioinformatics
Expertise in microscopy, generating mouse knockouts or neuronal culture
Previous experience analyzing omics datasets
Familiarity with statistics and optimal study design
Apply here online. Please be sure to upload a cover letter and Resume or CV.
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or firstname.lastname@example.org.
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm