A postdoctoral research position is available for a highly motivated individual to study the posttranslational regulation of c-Myc oncoprotein and ribosome biogenesis-associated proteins in cells and in vivo using genetic mouse models. Our overall goal is to understand molecular mechanisms underlying the regulation of the c-Myc oncogenic and the p53 tumor suppressor pathways and their implication in ribosome biogenesis and human cancer. Multidisciplinary approaches including molecular, cellular and biochemical, and mouse genetic analyses will be used. Candidates with Ph.D. and/or M.D. degrees and intensive training in the areas of molecular biology, biochemistry and cell biology are encouraged to apply.

Responsibilities include:

• Plans, conducts, and completes laboratory experiments. Performs primary molecular genetic techniques including PCR, DNA and RNA assays, Western blot, Northern and Southern blot analysis, protein purification, enzymatic assays, fluorescent and light microscopy, mouse handling and tissue collection and analysis including IHC staining.
• Collects, records organizes and verified the accuracy of data. Conducts literature search and summarizes information in an appropriate format for a particular study; Documents and interprets results of experiments and reports to principal investigator. Presents data at lab meetings and participates in journal club and research group meetings.
• Assists in the daily operation of the lab including hazardous waste disposal, sterilization of equipment, general lab equipment maintenance, and preparation of media and buffers. Operates a variety of instruments and scientific equipment. Independent design and implementation of experiments and assays as well as assuring compliance with established safety procedures
• Supervisory responsibilities over lab technicians and students as well as the general management of the lab

The appointee shall provide services as assigned by the supervisor in furtherance of the universitys missions and goals of teaching, research, patient care, outreach and public service. There will be cell biology, biochemistry and animal work involved.

• PhD, MD or MD/PhD degree in related field (with a strong molecular biology background)
• Soundjudgment in taking independent action, seeking advice as necessary.
• Demonstrates creativity and problem solving ability for assuming responsibility for specific components of research project
• Requires occasional supervision

• PhD with experience in Molecular biology, biochemistry or cancer biology
• Experience in mouse genetics

For consideration, please upload CV with a cover note indicating the particulars of your background that make you a suitable candidate. Also indicate your primary future research interests.

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