A postdoctoral research position is available for a highly motivated individual to study the posttranslational regulation of c-Myc oncoprotein and ribosome biogenesis-associated proteins in cells and in vivo using genetic mouse models. Our overall goal is to understand molecular mechanisms underlying the regulation of the c-Myc oncogenic and the p53 tumor suppressor pathways and their implication in ribosome biogenesis and human cancer. Multidisciplinary approaches including molecular, cellular and biochemical, and mouse genetic analyses will be used. Candidates with Ph.D. and/or M.D. degrees and intensive training in the areas of molecular biology, biochemistry and cell biology are encouraged to apply.
Plans, conducts, and completes laboratory experiments. Performs primary molecular genetic techniques including PCR, DNA and RNA assays, Western blot, Northern and Southern blot analysis, protein purification, enzymatic assays, fluorescent and light microscopy, mouse handling and tissue collection and analysis including IHC staining.
Collects, records organizes and verified the accuracy of data. Conducts literature search and summarizes information in an appropriate format for a particular study; Documents and interprets results of experiments and reports to principal investigator. Presents data at lab meetings and participates in journal club and research group meetings.
Assists in the daily operation of the lab including hazardous waste disposal, sterilization of equipment, general lab equipment maintenance, and preparation of media and buffers. Operates a variety of instruments and scientific equipment. Independent design and implementation of experiments and assays as well as assuring compliance with established safety procedures
Supervisory responsibilities over lab technicians and students as well as the general management of the lab
The appointee shall provide services as assigned by the supervisor in furtherance of the universitys missions and goals of teaching, research, patient care, outreach and public service. There will be cell biology, biochemistry and animal work involved.
PhD, MD or MD/PhD degree in related field (with a strong molecular biology background)
Soundjudgment in taking independent action, seeking advice as necessary.
Demonstrates creativity and problem solving ability for assuming responsibility for specific components of research project
Requires occasional supervision
PhD with experience in Molecular biology, biochemistry or cancer biology
Experience in mouse genetics
For consideration, please upload CV with a cover note indicating the particulars of your background that make you a suitable candidate. Also indicate your primary future research interests.
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or email@example.com.
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm