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Post Doctoral Research Opportunities
Albert Einstein College of Medicine
| LIST OF POST DOCTORAL RESEARCH CAREER OPPORTUNITIES: When applying, please make sure to reference the number that corresponds to the job posting you are interested in. Department Name: CELL BIOLOGY The research in the Guo lab focuses on stem cell plasticity and epigenetic regulation of mammary stem cells and cancer stem cells, as well as the impact of stem cell pathways on turmor immune microenvironment. We use a wide range of genomics/epigenomics methods, CRISPR genome editing, organoid culture, and in vivo mouse models. Contact email: wenjun.guo@einsteinmed.org Reference Number EINSTEIN PD 2 Department Name: GENETICS A postdoctoral position in the area of chromatin structure, transcription, signaling, developmental biology, genomics and bioinformatics. The research projects are focused on mammalian eye development to examine molecular mechanisms underlying embryogenesis, transcriptional control, chromatin dynamics and 3D-nuclear organization, activities of specific gene regulatory networks, and visualization of mRNA cycle and mRNA:RNA-binding protein interactions. Contact email: ales.cvekl@einsteinmed.org Reference Number EINSTEIN PD 3 Department Name: GENETICS The Zhou lab research focuses on molecular mechanisms of cardiovascular development. Areas of interest include genetic and epigenetic basis of cardiac cell specification and differentiation during development, heart disease, and regeneration (Cell, 23178125; Nature, 29743679, 25119045, 20596014; Eur Heart J, 26491108; Circ Res, 21597012; Nat Commun, 28924218, 29215012; PNAS, 25848038; Dev Cell, 29056552, 25625206; Annual Review Physiology, 27959615). Contact email: bin.zhou@einsteinmed.org Reference Number EINSTEIN PD 4 Department Name: NEUROSCIENCE The Ross lab studies neural circuit mechanisms governing the interaction of stress with fundamental motivated behavior, specifically focusing on the mechanisms of neuromodulators and hormones involved in dynamic homeostatic processes. We are interested in how these processes may underlie diseases of metabolism and mental health such as obesity or anorexia nervosa. Prior experience in at least one of these technical areas of expertise is preferred: calcium imaging/in vivo photometry, mouse behavioral tasks, molecular biology, high dimensional analyses of neuronal data (or biological data in general), electrophysiology, 2-photon microscopy, computer programming and electronics. For more information, please see: https://rosslab.einsteinmedneuroscience.org/research/. Contact email: Rachel.ross@einsteinmed.org Reference Number EINSTEIN PD 5 Department Name: GENETICS Our research is focused on molecular mechanisms of cardiomyopathy and heart failure. Specific areas of interest include genetic, epigenetic, and long noncoding RNA mechanisms of gene regulation (myocytes, endothelial cells, and fibroblasts) and cardiomyopathy. Our relevant publications include Nature (PMID: 25119045; 20596014; 25119037; 20130577), Cell (15339668); Circulation Research (18723445; 21293009), PNAS (23319608; 27601681), Nature Comm. (28924218; 29215012), Developmental Cell (23602386; 20816797), Annual Review Physiology (22035349), and Nature Review Cardiology (25855606). Contact email: chingpin.chang@einsteinmed.org Reference Number EINSTEIN PD 6 Department Name: MOLECULAR PHARMACOLOGY The area of research is in deciphering physiological functions of novel bacterial species isolated in the lab using basic microbial genetic techniques. The postdoctoral fellow should have advanced knowledge of microbial genetic techniques like CRISPR-Cas9, transposon, phage mediated mutants in bacteria. Additionally, should have training or skill in large scale data management and analysis of the microbiome by 16S/metagenomics/metatranscriptomics (e.g., PICRUSt). Contact email: Sridhar.mani@einsteinmed.org Reference Number EINSTEIN PD 7 Department Name: BIOCHEMISTRY The Sidoli lab is looking for a postdoctoral researcher to work on state-of-the-art mass spectrometry, innovative cell culture models and unusual sample collecting methods (e.g., breath biopsies) to investigate chromatin state in health and disease. Details on the position: https://jobrxiv.org/job/albert-einstein-college-of-medicine-27778-postdoc-in-chromatin-biology-proteomics-and-innovative-cell-culture-models/ Contact email: simone.sidoli@einsteinmed.org Reference Number EINSTEIN PD 8 Department Name:Bronx-Einstein Training in Teaching and Research (BETTR) program The IRACDA-BETTR NIH-sponsored postdoctoral training program is designed to help postdocs obtain tenure-track faculty positions and emphasizes training in research and mentored undergraduate teaching. Our teaching partners are Lehman College and Hostos Community College, two Hispanic-serving colleges located in the Bronx.This three year program provides 75% support for research activities and 25% for mentored teaching. Per NIH criteria, applicants must be U.S. citizens or Green Card holders, and must be within their first two years of postdoctoral training. For more information, see IRACDA/BETTR on the Einstein homepage. Contact email: barbara.birshtein@einsteinmed.org and/or dianne.cox@einsteinmed.org Reference Number EINSTEIN PD 9 Department Name: NEUROSCIENCE The Batista-Brito lab investigates how postnatal development of inhibitory function shapes the way information is processed in the brain in the context of health and disease. Cortical function depends on the adaptive function of brain areas comprised of many types of cells and synaptic connections that develop on a long timescale. During development, neural networks must grow from a state of zero connectivity to the precisely interconnected circuits characteristic of the adult brain. The activity of GABAergic inhibitory neurons during postnatal development is likely to mediate synaptic refinement, reducing synchrony and enhancing precision in the mature network. Accordingly, dysregulation of GABAergic interneurons has been linked to several neurodevelopmental disorders. We use a powerful combination of methods, including single-cell genetic profiling, mouse genetics, cell-type specific manipulation of neuronal activity, in vivo electrophysiology, in vivo 2-photon imaging, and behavioral analysis, in order to functionally dissect the developmental impact of specific sources of inhibition on cortical processing and perception. This research illuminates how cortical functions are altered in neurodevelopmental disorders, with particular focus opn schizophrenia and autism. Contact email: renata.brito@einsteinmed.org Reference Number EINSTEIN PD 10 Department Name: ANATOMY AND STRUCTURAL BIOLOGY The Verkhusha lab is interested in the development and application of molecular probes, such as biosensors and optogenetic tools, for monitoring and controlling biological processes in cells and animals. Two postdoctoral positions are available A: A molecular biologist interested in engineering fluorescent protein-based biosensors and characterizing them both in vitro and in cultured cells. B: A neuroscientist interested in imaging with advanced biosensors for the optogenetic control of activity and molecular processes in neurons, as well as cellular electrophysiology, electric field stimulation, optogenetics and calcium imaging. Contact email: postdoc.einstein@gmail.com Reference Number EINSTEIN PD 11A or 11B Department Name: BIOCHEMISTRY Postdoctoral positions are immediately available in the Gavathiotis Laboratory at Albert Einstein College of Medicine, New York City. Our laboratory investigates cell death and cell survival pathways such as apoptosis, selective autophagy, mitochondrial dynamics and oncogenic signalingwith the goal to characterize novel biological mechanisms that contribute to cancer and other diseases. We harness mechanistic and structural insights to discover first-in-class chemical probes and develop novel therapeutics that enable applications with translational impact. We currently study different protein-protein interactions including BCL-2 family proteins and mitochondrial proteins as well as protein kinases: Nat. Comms. 2020 PMID:32873792, Nat. Cancer 2020 PMID:32776015, Nat. Chem. Biol. 2019 PMID:30718816, Science 2018 PMID: 29674596, Cancer Cell 2017 PMID: 29017059, Mol. Cell 2016 PMID: 27425408, Cancer Cell 2016 PMID: 27523909. Contact email: evripidis.gavathiotis@einsteinmed.org Reference Number EINSTEIN PD 12 Department Name: NEUROSURGERY The Eskandar lab studies cortical-subcortical circuits and their role in learning, decision-making, and addiction. We perform micro-electrode recordings and micro-stimulation in experimental animals performing a variety of cognitive tasks and in humans performing parallel tasks, while implanted with electrodes for the treatment of Parkinson disease or epilepsy. This translational approach supports our over-arching goal of developing novel neuro-modulatory therapies for patients suffering from cognitive impairment, substance or behavioral addictions, and other neuropsychiatric disorders. Contact email: eskanda@montefiore.org Reference Number EINSTEIN PD 13 Department Name: PSYCHIATRY The Child Outpatient Psychiatry Division, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY is accepting applications for a one-year, full-time Postdoctoral Psychology Fellowship in the Connecting and Reflecting Experience (CARE) program for 2021-2022. The CARE clinical and research program is a developmentally informed, bi-generational, transdiagnostic specialty program that offers mentalizing-focused group treatment to parents of children from birth 18 years of age. This unique fellowship will follow a scientist-practitioner model, providing intensive training in the implementation, evaluation, and dissemination of mentalizing-focused group parenting interventions that aim to dismantle the intergenerational transmission of maltreatment trauma in marginalized and underprivileged communities. Contact email: azayde@montefiore.org Reference Number EINSTEIN PD 14 Department Name: MEDICINE and MICROBIOLOGY AND IMMUNOLOGY A position is open for the study of human protective antibodies against M. tuberculosis. This will be especially of interest for applicants who want to expand or gain experience in translational research. Specific interests of the laboratory include understanding the role of antibodies to M. tuberculosis in patients at various states of infection. These include i) large scale tuberculosis serology studies using innovative techniques to identify both antibodies that can serve as tuberculosis biomarker as well as antibodies with protective functions, ii) isolation and generation of polyclonal and monoclonal human antibodies to M. tuberculosis antigens, and iii) detailed studies of antibody mechanism against M. tuberculosis in vitro and in vivo. Candidates should have a strong background in Immunology and/or Microbiology. Contact email: Jacqueline.Achkar@einsteinmed.org Reference Number EINSTEIN PD 15 Department Name: NEUROLOGICAL SURGERY We aim to engineer treatments for disorders of visuospatial learning and memory. To achieve this aim, we perform studies to better our understanding of visuospatial learning and memory functions. We utilize advanced electrophysiological techniques to examine the circuitry of brain structures that are critical for these functions. Contact email:nathaniel.killian@einsteinmed.org Reference Number EINSTEIN PD 16 Department Name: NEUROSCIENCE The Castillo lab studies how neural activity controls the strength of synaptic connections in the brain -- a process known as synaptic plasticity -- and how dysregulation of this process contributes to brain disease states. To this end, we use a combination of experimental approaches, including electrophysiology, optogenetics, two-photon laser microscopy, in vivo calcium imaging, behavioral analyses, and a wide-range of molecular approaches to probe and manipulate specific neural circuits. A postdoctoral position is immediately available to investigate how experience in the form of learning paradigms leads to long-term changes at hippocampal synapses. Prior expertise in any of the following experimental approaches is a plus: electrophysiology, in vivo recordings/calcium imaging, computer programming and rodent behavioral tests. For more information, see: https://www.einstein.yu.edu/faculty/8363/pablo-castillo/ and https://einstein.pure.elsevier.com/en/persons/pablo-e-castillo Contact email: pablo.castillo@einsteinmed.org Reference Number EINSTEIN PD 17 A As member of the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (IDDRC), the Castillo lab is investigating how loss of function in Fragile X Mental retardation protein (FMRP), which causes Fragile X Syndrome (FXS), alters synaptic structure and function. A postdoctoral position is immediately available to investigate the role of FMRP at excitatory and inhibitory synapses both in the normal brain and in an animal model of FXS. Prior expertise in electrophysiology, molecular biology and confocal microscopy is a plus. For more information, see: https://www.einstein.yu.edu/faculty/8363/pablo-castillo/ and https://einstein.pure.elsevier.com/en/persons/pablo-e-castillo Contact email: pablo.castillo@einsteinmed.org Reference Number EINSTEIN PD 17 B Department Name: NEUROSCIENCE The Jordan Lab recently identified patients around the world presenting with a spectrum of neurodevelopmental phenotypes, including autism, speech apraxia, and intellectual disability, and which is caused by monogenic deletions of the ANKS1B gene. ANKS1B encodes for AIDA-1 protein, a highly abundant component of neuronal excitatory synaptic junctions that regulates NMDA receptor (NMDAR) function. A position is available to use animal and human models to analyze NMDAR in patient neurons, elucidate mechanisms linking AIDA-1 to NMDAR function, and identify disease-relevant cellular and molecular pathways underlying this novel disorder. Contact e-mail: bryen.jordan@einsteinmed.org Reference Number EINSTEIN PD 18 Department Name: PEDIATRICS The Department of Pediatrics at Einstein and Childrens Hospital at Montefiore (PI: Marina Reznik, MD, MS) is looking for a postdoctoral research fellow to collaborate on population-based studies of childhood asthma. Examples of several current studies include implementation and evaluation of a multi-level clinic-based intervention to improve provider adoption of asthma guidelines and patient outcomes; cluster RCT of a school-based study of asthma management program; and cross-sectional study of provider prescription practices and pharmacy availability of spacer devices for asthma. The Postdoctoral Research Fellow will develop new scientific hypotheses and research questions to be addressed using data from existing datasets from clinical trials, including commonly available national datasets; conduct statistical analyses and draft manuscripts, reports and presentations; assist with grant applications; and oversee other ongoing clinical studies and research staff. Contact email: mreznik@montefiore.org Reference Number EINSTEIN PD 19 Department Name: NEUROSCIENCE The Laboratory for Computational Neuroscience (Coen-Cagli lab) invites applications for a postdoctoral position in the Department of Systems and Computational Biology and Department of Neuroscience at Albert Einstein College of Medicine.Our lab studies sensory processing in brains and machines. We study probabilistic representations of natural images, to understand visual perception and neural activity in visual-cortical populations. We combine theories of probabilistic neural coding, computer vision and machine learning algorithms, perceptual experiments, and primate and rodent neurophysiology through collaborations.Lab website:https://sites.google.com/site/rubencoencagli Contact email: Ruben.coen-cagli@einsteinmed.org Reference Number EINSTEIN PD 20 Department Name: MICROBIOLOGY AND IMMUNOLOGY Our laboratory utilizes innate immune factors to study HIV-1 uncoating, reverse transcription and nuclear import (PMID:32997983 and 32187548). To investigate these HIV-1 steps, we utilize virology, cell biology, biochemistry, immunology and mouse biology. We also pursue the development of therapeutics for emergent infectious viruses such as ZIKA and SARS-CoV-2 (PMID:31501074). Contact email: Felipe.Diaz-Griffero@einsteinmed.org Reference Number EINSTEIN PD 21 Department Name: NEUROSCIENCE The Kurshan Lab (www.kurshanlab.org) uses the nematode C. elegans to investigaes how synapses are built. The genetic and optical accessibility of the worm, combined with its sterotyped development, make it an ideal system in which to interrogate the molecular underpinning of synapse development. Using this model, we investigate how mutations in synaptic genes linked to neurodevelopmental disorders such as autism and schizophrenia contribute to the normal function of the synapse. Contact email: Peri.kurshan@einsteinmed.org Reference Number EINSTEIN PD 22 Department Name: SYSTEMS AND COMPUTATIONAL BIOLOGY Apostdoc positions are open for developing and employing computational techniques for designing specificity for protein interfaces in various disease-oriented applications. The research includes various aspects of method development to analyze, predict and design protein interfaces. The position is highly interdisciplinary and provides close collaborations with experimentalists with follow up translational applications.The ideal candidate holds a PhD degree in relevant fields (e.g. computational biology, chemistry, physics, applied mathematics) and has an extensive computational background in scripting and programming languages, familiar with Linux operating system. Has a strong working knowledge of principles of protein structures, familiar with bioinformatics programs and applications, including some experience with MD simulations. Contact email: Andras.fiser@einsteinmed.org Reference Number EINSTEIN PD 23 Department Name: BIOCHEMISTRY, MEDICINE AND OBSTETRICS & GYNECOLOGY AND WOMEN'S HEALTH The Charron Laboratory is interested in understanding the molecular basis of early life exposures that predispose offspring to metabolic disease and/or developmental disabilities. Our Bronx MomBa Study on babies recruited at birth and followed through 24 months of age for early childhood obesity and developmental delay inorporates molecular epigentic, transcriptomic, and functional assessments of immune cells and interactions with the metabolome and gut microbiome. We use mouse models to rigorously test dietary and therapeutic interventions for the ability to modify the developmental environment and provide life long improvements in metabolic and behavioral outcomes in offspring. Contact email: Maureen.charron@einsteinmed.org Reference Number EINSTEIN PD 24 Department Name: RADIOLOGY Our research focuses on applying medical imaging methods and analysis methods (include machine learning) to study health and disease, aiming at early detection, accurate diagnosis, evaluation and prediction of disease courses and treatment responses. We collaborate closely with clinicians to solve clinically impactful problems. Some of projects include: i) Effects of chemotherapy on neurocognitive function in cancer patients, ii) MRI studies of breast cancer and lymph node metastasis and treatment response, iii) MRI study of neurodegenerative disease and acquired brain injuries, and iv) COVID-19 and COVID-19 sequela.https://sites.google.com/view/duong-lab/ Contact email: Tim.duong@einsteinmed.org Reference Number EINSTEIN PD 25 Department Name: NEUROSCIENCE AND GENETICS AND STEM CELL INSTITUTE The Hebert lab is developing protocols for repairing the adult neocortex when it is damaged due to disease or aging. In one set of projects, the lab studies how donor cell populations comprised of multiple subtypes can recapitulate normal tissue cytoarchitecturewhen transplanted in layers. In another set of projects, the lab is studying how transplanted microglia can be used as a delivery vehicle for biologics to treat neurodegeneration. For more info, please visit:https://hebertlab.einsteinmedneuroscience.org/ Contact email: Jean.hebert@einsteinmed.org Reference Number EINSTEIN PD 26 Department Name: NEUROSCIENCE AND OTORHINOLARYNGOLOGY A joint postdoctoral research fellow position is available in the Departments of Neuroscience and Radiology. Using brain electrophysiology (EEG) and neuroimaging (fMRI) techniques, our newly-funded NIH project is investigating chronic effects of chemotherapy treatment on brain development and cognitive functioning in childhood leukemia survivors (ages 5-12 years). Contact email: elyse.sussman@einsteinmed.org & mark.wagshul@einsteinmed.org Reference Number EINSTEIN PD 27 Department Name: GENETICS My lab is interested in understanding how mutations in the chromatin modifying enzyme KDM5 lead to intellectual disability. To do this, we combine transcriptome and epigenomic analyses with cell biological and behavioral assays in the model organism Drosophila. Contact email: Julie.secombe@einsteinmed.org Reference Number EINSTEIN PD 28 Department Name: CELL BIOLOGY Alphaviruses are enveloped RNA viruses that include important human pathogens such as Chikungunya virus. We have developed robust multidisciplinary tools to characterize the molecular interactions and mechanisms of virus and host cell components during the virus lifecycle. Many important questions remain unsolved, and current research projects include the study of virus assembly, trafficking, budding, and cell-to-cell transmission. Contact email: margaret.kielian@einsteinmed.org Reference Number EINSTEIN PD 29 Department Name: GENETICS The Lachman lab uses induced pluripotent stem cell (iPSC) technology to model intellectual Contact email: herb.lachman@einsteinmed.org Reference Number EINSTEIN PD 30 Department Name: GENETICS AND PEDIATRICS Join our childhood cancer research team and focus on an exciting new opportunity to evaluate novel approaches to inhibiting telomere maintenance mechanisms. Apply your cellular and molecular biology skills, learn bioinformatics, and see real-time results translate into the next clinical research study for relapsed neuroblastoma. We value teamwork, integrity, ambition, and intellectual curiosity(https://www.einsteinmed.org/faculty/13846/daniel-weiser/) Contact email: daniel.weiser@einsteinmed.org Reference Number EINSTEIN PD 31 Department Name: ANATOMY & STRUCTURAL BIOLOGY The Verkhusha laboratory at the Albert Einstein College of Medicine Contact email: postdoc.einstein@gmail.com & daria.shcherbakova@einsteinmed.org Reference Number EINSTEIN PD 32 Department Name: MICROBIOLOGY & IMMUNOLOGY Kalpana Laboratory studies molecular mechanisms of HIV-1 replication, HIV-1 latency and Cancer and use this information to develop novel therapeutic and diagnostic strategies for AIDS and Cancer. By investigating the structure-function analysis, protein-protein and protein-RNA interactions of INI1/SMARCB1, a tumor suppressor and a host factor that binds to HIV-1 integrase, we have discovered that structural mimicry of proteins to RNA that has led to the development of novel therapeutic strategies for HIV-1. Furthermore, by applying state-of-the art technologies including single molecule RNA-FISH and single cell RNA-seq, we are studying HIV-1 latency and SARS-CoV2 replication. Contact email:ganjam.kalpana@einsteinmed.org Reference Number EINSTEIN PD 33 Department Name: CELL BIOLOGY The Pamela Stanley lab identifys specific roles for gylcans during spermatogenesis. The Stanley lab has shown that MGAT1 and complex N-glycans are essential for spermatogenesis. Conditional deletion ofMgat1 in spermatogonia results in spermatid fusion and no sperm. Roles for specific glycoproteins in the spermatogenesis defect will be investigated. Publications are linked to the laboratory homepage athttp://www.einstein.yu.edu/departments/cell-biology/faculty/stanley/home/ Contact email: gianette.fata@einsteinmed.org Reference Number EINSTEIN PD 34 Department Name: NEUROSCIENCE & PEDIATRICS (NEONATOLOGY) The Ballabh laboratory is seeking highly motivated, successful, and creative individual(s) with a background in neuroscience. The post-doctoral fellow will be participating in translational research on animal models of intraventricular hemorrhage (IVH) of prematurity.The main focus of our laboratory is to study underlying mechanisms and developing novel therapies for prematurity- and IVH-induced brain injuries. We employ a multidisciplinary approach and integrate histology, neuroimaging, genomics, MRI and neurobehavioral studies to answer our research question.Please see our lab website for more information: https://ballabhlab.einsteinmedneuroscience.org/ Contact email: praveen.ballabh@einsteinmed.org Reference Number EINSTEIN PD 35 Department Name: CELL BIOLOGY A postdoctoral position is available at Albert Einstein College of Medicine in the laboratory of Dr. Art Skoultchi, Professor and Chair of Cell Biology. The goal is to understand the roles of H1 linker histones in chromatin structure and function, gene regulation and cancer. We have prepared a unique series of knock-out mice and ES cell lines lacking specific H1 histones. Our studies have revealed roles for H1 histones in gene regulation, the epigenetic landscape and nuclear organization. Contact email: arthur.skoultchi@einsteinmed.org Reference Number EINSTEIN PD 36 Department Name: GENETICS Laboratory ofDr. Masako Suzuki, DVM, PhD A postdoctoral position in the area of Developmental Origins of Health, lineage commitment of stem cells, transcription, signaling, developmental biology, genomics, and bioinformatics. The research projects are focused on how the offspring remembers the exposure status of maternal micronutrient deficiency in the uterus and how it links to the disease risks of offspring later in life. Contact email: masako.suzuki@einsteinmed.org Reference Number EINSTEIN PD 37
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