Essential Functions: This position will be involved in a NIH-funded project to study the roles of microRNAs in ocular immunity and in bacterial keratitis using transgenic mouse models and human corneal samples. The project also will explore the potential of miRNAs as therapeutic targets and develop miRNA-based therapy for bacterial keratitis and related immune/inflammatory diseases. This position will also have opportunities to explore the roles of miRNAs in other ocular diseases, including inherited retinal degeneration, diabetic retinopathy, and diabetes. The research will be conducted with comprehensive genetic, cellular and molecular biology and immunological techniques, including flow cytometry, cell sorting, cell culture, gene expression profiling by real time PCR, RNA seq, single cell seq, and immunohistochemistry.Principle Duty and Responsibilities:Plan and design of experiments.Conduct the experiments and data analysis. Prepare manuscripts and assist in grant writing.Present data in lab meeting, local and national conferences.Assist in training of students.
Qualifications: Qualified candidates must have a MD and/or PhD degree(s) in ocular sciences, immunology, molecular biology, molecular genetics and cell biology. Knowledge and skills required: Knowledge and techniques in cell biology, e.g. cell culture, immunohistochemistry, Western blot, in situ hybridization. Knowledge and technique in molecular biology, e.g. DNA, RNA isolation, PCR, RT-PCR. Knowledge and skills in microscopy.Computer skills, including word processing, excel, power point, photoshop, internet browsing.Good communication and organization skills.
Internal Number: 76_208302
About Wayne State University
Founded in 1868, Wayne State University is a nationally recognized metropolitan research institution offering more than 400 academic programs through 13 schools and colleges to nearly 32,000 students. Wayne State?s main campus in Midtown Detroit comprises 100 buildings over nearly 200 acres; its five extension centers offer higher education to people throughout Southeast Michigan. Wayne State is dedicated to preparing students to excel by combining the academic excellence of a major research university with the practical experience of an institution that by its history, location and diversity represents a microcosm of the world we live in. Reflecting its location and the excellent international reputation of its graduate schools, particularly in the sciences, Wayne State boasts the most diverse student body among Michigan?s public universities. Its students represent 49 U.S. states and more than 60 countries.