The Feinberg School of Medicine’s Department of Dermatology at Northwestern University invites applications for postdoctoral candidates with strong research skills and an interest in utilizing bioinformatics for basic research, preclinical and translational big data sets. The position involves working with the PI of an NIH-funded skin disease research center that leverages clinical and bench research towards translation. Access to a wide range of human biomaterials to uncover transcriptional, proteomic, metabolomic, and lipidomic alterations. Follow up on bioinformatic data involves taking candidates into the basic science lab for better defining and moving discoveries forward towards drug discovery or repurposing existing medications in preclinical and ultimately clinical trials.
The research lab’s three main areas of focus are: a) using topically-delivered nanotechnology towards developing new targeted therapies for skin disorders; b) understanding the mechanism(s) of peripheral sensory neuropathy in inflammatory skin disorders (such as psoriasis and eczema) and diabetic wounds; and c) determining the mechanism by which obesity exacerbates inflammatory disease.
The ideal candidate will have some skills from PhD research or an early postdoctoral fellowship but will be seeking additional skills (in both bench research and bioinformatics) through this fellowship. Research projects will involve processing big data sets in transcriptomics, proteomics, metabolomics, and lipidomics and relating these measures to preclinical and clinical outcomes. Previous programming skills in MATLAB, R, and/or Python are required. Must have excellent communication skills.
Lab-based basic science studies to complement big data findings; shared maintenance, ordering
Conducting computational laboratory experiments
Maintaining animals, breeding, genotyping for experiments
Help write grants
Supervising students and colleagues
Help write and prepare manuscripts
PhD or MD/PhD
PhD training in bioinformatics with experience in biochemistry, immunology, molecular or cell biology; alternate would be background in computer science and statistics
Proficiency with Word, Excel, Prism, MATLAB R and/or Python
Experience with biochemistry and/or immunology techniques
Experience in biostatistics
Experience in working with mouse models of disease
Understanding of receptor signaling pathways
Understanding of skin biology as a bonus, but not required
Competency in human and preclinical based bioinformatic approaches
Familiar with biochemistry and/or molecular biology techniques
Eagerness to learn
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 39300
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.