| Department: MED-Dermatology
Salary/Grade: RES/ Job Summary: The Feinberg School of Medicine’s Department of Dermatology at Northwestern University invites applications for postdoctoral candidates with strong research skills and an interest in utilizing bioinformatics for basic research, preclinical and translational big data sets. The position involves working with the PI of an NIH-funded skin disease research center that leverages clinical and bench research towards translation. Access to a wide range of human biomaterials to uncover transcriptional, proteomic, metabolomic, and lipidomic alterations. Follow up on bioinformatic data involves taking candidates into the basic science lab for better defining and moving discoveries forward towards drug discovery or repurposing existing medications in preclinical and ultimately clinical trials. The research lab’s three main areas of focus are: a) using topically-delivered nanotechnology towards developing new targeted therapies for skin disorders; b) understanding the mechanism(s) of peripheral sensory neuropathy in inflammatory skin disorders (such as psoriasis and eczema) and diabetic wounds; and c) determining the mechanism by which obesity exacerbates inflammatory disease. The ideal candidate will have some skills from PhD research or an early postdoctoral fellowship but will be seeking additional skills (in both bench research and bioinformatics) through this fellowship. Research projects will involve processing big data sets in transcriptomics, proteomics, metabolomics, and lipidomics and relating these measures to preclinical and clinical outcomes. Previous programming skills in MATLAB, R, and/or Python are required. Must have excellent communication skills. Specific Responsibilities: - Lab-based basic science studies to complement big data findings; shared maintenance, ordering
- Conducting computational laboratory experiments
- Maintaining animals, breeding, genotyping for experiments
- Help write grants
- Supervising students and colleagues
- Help write and prepare manuscripts
Minimum Qualifications: - PhD or MD/PhD
- PhD training in bioinformatics with experience in biochemistry, immunology, molecular or cell biology; alternate would be background in computer science and statistics
Minimum Competencies: - Proficiency with Word, Excel, Prism, MATLAB R and/or Python
- Experience with biochemistry and/or immunology techniques
- Experience in biostatistics
Preferred Qualifications: - Experience in working with mouse models of disease
- Understanding of receptor signaling pathways
- Understanding of skin biology as a bonus, but not required
Preferred Competencies: - Competency in human and preclinical based bioinformatic approaches
- Familiar with biochemistry and/or molecular biology techniques
- Eagerness to learn
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
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