Join a Team that Lives to Improve Lives People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen.
The following opportunity exists in our South San Francisco, CA headquarters:
Scientist / Sr. Scientist, Drug Metabolism and Pharmacokinetics
The Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech is seeking a highly motivated leader who will be supporting small molecule projects in discovery and development.
The DMPK group is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state of the art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
The individual would lead the DMPK project strategy, design and execute non-clinical studies in a highly collaborative environment. This position will require knowledge of ADME, with focus on PK and PK/PD modeling.
The individual will be involved in the following activities as part of their role:
Representation of DMPK at interdisciplinary project teams
Pharmacokinetic & pharmacodynamic data analysis and modeling
Author report/sections for regulatory filings, i.e., IND and NDA filings
Managing and mentoring scientists
A PhD degree in pharmacokinetics, drug metabolism or other relevant field
Good understanding of ADME with proven scientific expertise in this field
Good communication, managerial and organizational skills and the ability to work in multifunctional teams are essential
5-10 years of relevant pharmaceutical industry experience as a DMPK project leader / representative
Familiarity with various modeling software packages such as MatLab, ADAPT, SAAMII and NONMEM is highly desired
A Job with Benefits Beyond the Benefits A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
The next step is yours. To apply today, click on the "Apply online" button.
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At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.