Join a Team that Lives to Improve Lives People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen.
The following opportunity exists in our South San Francisco, CA headquarters:
The Preclinical and Translational PKPD (PTPK) Department at Genentech, Inc. is seeking a PhD level scientist who is driven to understand the pharmacokinetics (PK) and pharmacodynamics (PD) of novel drug candidates. The candidate will be responsible for investigating the pharmacokinetics, biodistribution, and PKPD relationships of novel therapeutics in preclinical models to identify optimal lead candidates for further development, and for translating preclinical PKPD information to patients to ensure appropriate dose/regimen decisions using state-of-the-art experimental and quantitative approaches. The candidate will be working in close partnerships across various functions including Research, Development Sciences, Clinical Sciences, Biostatistics, and Regulatory. The candidate will represent the department on cross-functional project teams as a PKPD representative and present PKPD results at cross-functional teams, department meetings, review committees, and conferences.
Who You Are
We are looking for individuals who are inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture.
A Ph.D. in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Biomedical Engineering or related discipline.
Minimum of 0+ years (for Associate Scientist) and 3+ years (for Scientist) of relevant PKPD experience and demonstrated impact on drug development and/or the PKPD scientific landscape.
Strong knowledge and experience in immunology, regenerative medicine, tumor immunology, fibrotic diseases, neurodegenerative diseases or oncology, are highly desired.
Strong knowledge and experience in PK and PK/PD of large molecule therapeutics (e.g., monoclonal antibodies, bispecifics, fusion proteins, antibody-drug conjugates, etc.) and/or RNA therapeutics are highly desired.
Working knowledge of PK/PD software (e.g., WinNonlin, R, NONMEM, ADAPT II, SimBiology, etc) and the ability to analyze and critically assess PK/PD data is essential.
The candidate should have experience working on cross-functional teams, demonstrate excellent communication skills, and have the ability to work independently and effectively.
Modeling and simulation (M&S) experience is a plus.
A Job with Benefits Beyond the Benefits A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
The next step is yours. To apply today, click on the "Apply online" button.
Additional Salary Information: Depends On Experience