At Boston Children's Hospital, success is measured in patients treated, parents comforted and teams taught. It's in discoveries made, processes perfected, and technology advanced. In major medical breakthroughs and small acts of kindness. And in colleagues who have your back and patients who have your heart. As a teaching hospital of Harvard Medical School, our reach is global and our impact is profound. Join our acclaimed Department of Medicine - Genetics and discover how your talents can change lives. Yours included.
Our laboratory is focused on improving the understanding of the underlying genetics of neurodevelopmental disorders and on using genomic tools to develop therapeutics for diseases affecting the central nervous system. We approach genetics questions using a combination of clinical and evolutionary methodologies including the following specific areas. First, development of new methodologies which examine mutations often missed by traditional genetic testing. Second, rigorous large-scale genetic data generation and functional testing of coding and regulatory mutations. Third, evolutionary analysis of coding and noncoding regions regulating human neural development. These approaches inform our translational goal to design and deliver genome-guided therapeutics for seriously ill children.
This Research Assistant I will be responsible for:
According to prescribed protocols and assigned schedules, performing a variety of routine laboratory experiments and procedures, utilizing standard laboratory equipment, recording and checking results for completeness and accuracy.
Assisting in troubleshooting procedures if experimental results are unexpected or quality of specimens is poor.
Performing the following techniques typically required for the laboratory/study: Maintaining records of results and methodologies in a log of work performed. Maintaining equipment, lab area and supplies in a neat professional manner. Sterilizing and cleaning glassware, preparing media and other materials using appropriate procedures. Inventorying supplies alerting supervisor to needed supplies, or mixing standard reagents. Processing order for supplies and/or animals.
Attending courses in safety procedures for handling, storage and disposal of biohazardous, flammable, corrosive and toxic materials. Carrying out all laboratory activities in compliance with applicable regulations and protocols.
Conducting literature searches and reviews, compiling information for journals and suggesting uses for new techniques to the P.I. Attending courses, lectures and conferences to further own knowledge of research and laboratory techniques, consulting with other researchers and technicians to exchange information.
Contributing to the team within and between departments and organizations.
To qualify, you must have:
The knowledge of theories, principles, and concepts acquired through completion of a Bachelor's degree in a science.
Experience with next generation sequencing, especially human exome and genome sequencing and RNAseq is a plus. R/MySQL/Python skills are preferred.
Strong organizational skills.
An interest in human genetics, specifically related to neurodevelopmental disorders and neurodegenerative diseases.
Boston Children's Hospital offers competitive compensation and unmatched benefits, including affordable health, vision and dental insurance, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition Reimbursement, and discounted rates on T-passes (50% off). Discover your best.
Boston Children's Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability.
Internal Number: 2900462
About Boston Children's Hospital
Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care. As one of the largest pediatric medical centers in the United States, Children's offers a complete range of health care services for children from birth through 21 years of age.