Summary Description: Columbia University's Department of Medicine, Division of Cardiology, The Reilly Cardiovascular Precision Medicine research group seeks a post-doctoral research scientist. The successful candidate will have grounding in human genetics, functional genomics and molecular biology in pursuit of the genetic and molecular basis of complex diseases. Ideally, the candidate will have training and experience in genetic discovery (e.g., GWAS, exome/DNA-seq, RNA-seq, ChIP-seq etc.) and related functional model systems (e.g. human induced pluripotent stem cells (iPSCs), gene editing, humanized mouse models cell modes.) He/she will pursue functional genomic studies of human loci for cardiometabolic traits. Projects are NIH-funded and require a post-doctoral lead on specific genetic loci and mechanisms for atherosclerosis and complex cardiometabolic traits and includes generation and analysis of cell and tissue specific genomic data (DNAseq, RNAseq, ChIPseq) cell signaling and biology in primary human cells and hIPSC-derived cells, including gene-editing and mouse models (knockout and transgenic) for cardiometabolic studies. The post-doctoral period is for a minimum of two years and the candidate will be mentored towards an independent academic career. An ability to work independently as well as in a strong team-science environment is required.
Minimum Qualifications: Requires a PhD, MD-PhD or equivalent doctoral training. Experience in human genetics, functional genomics and molecular biology including cell systems and mouse models of human cardiometabolic disease.
Preferred Qualifications: Experience with analysis and bioinformatics of genome wide data (SNP-GWAS, exome/whole genome data RNAseq, ChIPseq) e.g. in constitutional genomics; experience with primary cell and stem cell tools in functional genomics; experience with mouse models and in vivo phenotyping of vascular or metabolic traits.
As a member of the National Collegiate Athletic Association (NCAA) and the Council of Ivy Group Presidents (Ivy League), it is imperative that members of the Columbia University community, in all matters related to the intercollegiate athletics program, exhibit the highest professional standards and ethical behavior with regard to adherence to NCAA, Conference, University, and Department of Intercollegiate Athletics and Physical Education rules and regulations.
Columbia University is an Equal Opportunity/Affirmative Action employer.
Internal Number: 334_65714
About Columbia University
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