Summary Description: A post-doctoral research scientist position is available in the Department of Medicine, Division of Cardiology, with the Reilly group at Columbia University. The successful candidate will have grounding in human genetics, functional genomics and molecular biology in pursuit of the genetic and molecular basis of complex diseases. Ideally with training and experience in genetic discovery (e.g., GWAS, exome/DNA-seq, RNA-seq, ChIP-seq etc) and related functional model systems (e.g., human induced pluripotent stem cells, gene editing, humanized mouse models cell modes). He/she will pursue functional genomic studies of human loci for cardiometabolic traits. Projects are NIH-funded and require a post-doctoral lead on specific genetic loci for CAD and includes generation and analysis of cell and tissue specific genomic data (DNAseq, RNAseq, ChIPseq), cell signaling and biology in primary human vascular cell and hIPSC-derived vascular cells including gene-editing, and mouse models (knockout and transgenic) for vascular studies.
Minimum Qualifications: Requires a PhD, MD, PhD or equivalent doctoral training. Experience in human genetics, functional genomics and molecular biology including cell systems and mouse models of human cardiometabolic disease. Experience with analysis and bioinformatics of genome wide data (SNP-GWAS, exome/whole genome data, RNAseq, ChIPseq) e.g., in constitutional or cancer genomics; experience with primary cell and stem cell tools in functional genomics; experience with mouse models and in vivo phenotyping of vascular or metabolic traits. Comfortable in team science environment that includes laboratory, computational, biostatistical and clinical applications and interactions.An ability to work independently as well as in a strong team-science environment are required.
Preferred Qualifications: Prior post-doctoral experience (1-2 years) in relevant areas a plus but not required.
As a member of the National Collegiate Athletic Association (NCAA) and the Council of Ivy Group Presidents (Ivy League), it is imperative that members of the Columbia University community, in all matters related to the intercollegiate athletics program, exhibit the highest professional standards and ethical behavior with regard to adherence to NCAA, Conference, University, and Department of Intercollegiate Athletics and Physical Education rules and regulations.
Columbia University is an Equal Opportunity/Affirmative Action employer.
Internal Number: 334_62858
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.