Advertised Summary Job Description: Under the supervision of the Principal Investigator, the Senior Technician will work in a laboratory focused on the genetic and pathological underpinnings of neuromuscular diseases. They will be responsible to:
-Design and optimize assays for analyzing DNA from patients with neuromuscular disease, including Sanger sequencing, fragment size determination, and polymorphism genotyping. In conjunction with the PI, they will interpret the findings of these assays.
-Aggregate information on DNA abnormalities found in patients from various types of databases for the PI to consider in interpreting findings from patients.
-Assist the PI in processing and carefully storing donated tissues from patients with neuromuscular diseases. They will maintain accurate inventories of these tissues and with guidance, distribute tissues to collaborators.
-Perform basic histological preparation of human tissues, including fixing, sectioning, and staining using existing protocols and working with the PI to develop and optimize additional immune-histochemical methods as needed.
-Maintain laboratory equipment and records, perform quality control and quality assurance activities as needed.
-Perform miscellaneous functions required to maintain smooth operation of the laboratory such as clerical duties, reagent preparation and inventory control activities.
General Minimum Qualifications: Bachelor's degree in the following majors: biology, chemistry, biochemistry and medical laboratory technology and at least 1.5 years of related experience or equivalent in education, training and experience.
Additional Specific Minimum Qualifications: -Proficiency in Excel and use of Internet resources for literature searches and database mining. -Comfortable around deceased patient and their derived tissues/samples. -Excellent written and verbal communication skills. -Excellent interpersonal skills. -Ability to use good problem solving techniques. -Advanced organizational and analytical skills. -Demonstrated attention to detail. -Team-oriented and results-driven.
Preferred Qualifications: -1 year experience in tissue histology/immunohistochemistry -Familiarity with human genetic terminology -Experience in basic molecular biology techniques
As a member of the National Collegiate Athletic Association (NCAA) and the Council of Ivy Group Presidents (Ivy League), it is imperative that members of the Columbia University community, in all matters related to the intercollegiate athletics program, exhibit the highest professional standards and ethical behavior with regard to adherence to NCAA, Conference, University, and Department of Intercollegiate Athletics and Physical Education rules and regulations.
Columbia University is an Equal Opportunity/Affirmative Action employer.
Internal Number: 126_173506
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.