The Department of Psychiatry is seeking a specialist (cellular and molecular neurobiologist) in autism genetics lab for work with a human induced pluripotent stem cell (iPSC) model of autism. The successful applicant will be hard-working, self-motivated, a creative trouble-shooter, and a good team member. Abundant opportunities to use emerging technologies and to contribute to understanding the biological basis and therapeutic potential for autism.
Ph.D in Systemic Neurosciences with extensive knowledge of neuronal physiology.
Interdisciplinary training in human genetics and neurobiology.
At least 5 years hands-on experience in generation and maintenance of patient-derived iPSCs, characterization, differentiation of iPSCs to cell types of the neural lineage including glutamatergic/GABAergic neurons, astrocytes, and maintenance of long-term neural cultures.
Expertise in neurodevelopmental disease modeling using cell-based assays such as neuron morphometry, axon/dendrite extension, and synaptogenesis.
Expertise in designing shRNAs and knockdown of genes in iPSC-derived neurons.
Proficiency in cellular and molecular biology techniques such as Western blot, immunofluorescence, molecular cloning, viral vector design/use and qPCR.
Expertise in confocal microscopy, high-throughput imaging and analyses.
Excellent publication record in scientific journals.
Experience with cell culture, including both human iPSCs and neurons.
Neuroscience doctorate and 5 years postdoctoral experience or equivalent is desired.
UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
Internal Number: JPF02174
About University of California, San Francisco
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.